Overview
Don Rickles, John Leguizamo, and musical guest Erran Baron Cohen
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16 - 1Jarod Miller, Jason Lezak, Ra Ra Riot September 02, 2008 -
16 - 2Nicolas Cage, Vivica A. Fox, Delta Spirit September 03, 2008
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16 - 3Dr. Phil, Kevin Connolly, Adele September 04, 2008
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16 - 4Jerry O'Connell, Tim Gunn, Christian Lander September 05, 2008
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16 - 5Howie Mandel, Nastia Liukin, Bon Iver September 08, 2008
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16 - 6Keira Knightley, Tyler Perry, Bill Burr September 09, 2008
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16 - 7Curtis Jackson, Kaitlin Olson, Gym Class Heroes September 10, 2008
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16 - 8Serena Williams, Amy Sedaris, Meiko September 11, 2008
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16 - 9Eva Mendes, Luke Russert, The Fab Faux September 12, 2008
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16 - 10Samuel L. Jackson, Ricky Gervais, Marc Broussard September 15, 2008
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16 - 11Martha Stewart, Harland Williams, Kasey Chambers & Shane Nicholson September 16, 2008
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16 - 12Ray Liotta, Marc Maron,Loudon Wainwright III September 17, 2008
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16 - 13Anderson Cooper,Willie Nelson, Southside Johnny with La Bamba's Big Band September 18, 2008
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16 - 14Ice-T, Dwayne Wade, Shane Mauss September 19, 2008
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16 - 15Diane Lane, Patton Oswalt, Little Feat September 22, 2008
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16 - 16Billy Bob Thornton, Aasif Mandvi, Kenny Shopsin September 23, 2008
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16 - 17Jaime Pressly, Little Britain, Lenka Kripac September 24, 2008
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16 - 18Julianne Moore, Zachary Levi, Jakob Dylan September 25, 2008
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16 - 19Brooke Shields, Robert Reich, Amos Lee September 26, 2008
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16 - 20Bill Maher, Simon Pegg, The Watson Twins September 29, 2008 -
16 - 21Julia Louis-Dreyfus, Michael Cera, Nate Bargatze September 30, 2008
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16 - 22Robin Wright-Penn, Louis C.K., Department of Eagles October 01, 2008
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16 - 23Tom Arnold, Flavor Flav, Ben Folds October 02, 2008
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16 - 24Greg Kinnear. J.J. Abrams, Nick Cave and the Bad Seeds October 03, 2008
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16 - 25Felicity Huffman, Jason Sudeikis, Jenny Lewis October 06, 2008
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16 - 26Russell Crowe, Alicia Keys, Death Cab for Cutie October 07, 2008
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16 - 27Molly Shannon, Jason Ritter, Noah McCullough October 08, 2008
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16 - 28Dennis Quaid, Lance Mackey, Sarah McLachlan October 09, 2008
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16 - 29LL Cool J, Oliver Stone, Dead Confederates October 10, 2008
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16 - 30Christian Slater, Brian Posehn, Flobots October 13, 2008
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16 - 31Harry Connick, Jr., Richard Lewis, O.A.R. October 14, 2008
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16 - 32Bill Murray, Rob Corddry, Ray LaMontagne October 15, 2008
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16 - 33Josh Brolin, Shaun Ellis & Helen Jeffs, Nikka Costa October 16, 2008
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16 - 34Edward Norton, Chris "Ludacris" Bridges, Mike Birbiglia October 17, 2008
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16 - 35Charles Barkley, Justin Long, Annuals October 27, 2008
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16 - 36Tina Fey, Peter Sarsgaard, The Black Crowes October 28, 2008
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16 - 37Tracy Morgan, Paget Brewster, The Last Shadow Puppets October 29, 2008
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16 - 38Jada Pinkett-Smith, Jason Biggs, Pink October 30, 2008
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16 - 39Mary-Kate Olsen, Will Forte, Tom Nardone October 31, 2008
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16 - 40Brian Williams, Bill Bellamy, The Decemberists November 03, 2008
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16 - 41Dennis Hopper, Katt Williams, Phil Lesh & Friends November 05, 2008
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16 - 42Elvis Costello, Madeleine Albright, Lordi November 06, 2008
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16 - 43Ricky Gervais, Vera Farmiga, Chromeo November 07, 2008
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16 - 44Andy Richter, Jim Cramer, Tom Papa November 10, 2008
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16 - 45Seth Green, Artie Lange, Conor Oberst & The Mystic Valley Band November 11, 2008
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16 - 46Tom Brokaw, Frank Caliendo, Joshua Radin November 12, 2008
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16 - 47Paul Rudd, John Stamos, Boz Scaggs November 13, 2008
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16 - 48Masi Oka, Alan Zweibel, Rock of Ages November 14, 2008
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16 - 49Snoop Dogg, Brian Regan, Blitzen Trapper November 17, 2008
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16 - 50Jeff Corwin, Debra Messing, John Hodgman November 18, 2008
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16 - 51Martin Short, Sarah Vowell, Margot and the Nuclear So & So's November 19, 2008
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16 - 52Rosie O'Donnell, Becki Newton, Brian Wilson November 20, 2008
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16 - 53Kiefer Sutherland, Rachel Maddow, Vampire Weekend November 21, 2008
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16 - 54Hugh Jackman, Marge Klindera, Tom Morello November 24, 2008
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16 - 55Kanye West, Seth MacFarlane November 25, 2008
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16 - 56Ethan Hawke, Nikki Reed, Plain White T's November 26, 2008
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16 - 57Stephen Colbert, Keri Russell, The Lee Boys December 08, 2008
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16 - 58Hugh Laurie, Joel McHale, The Gaslight Anthem December 09, 2008
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16 - 59Jennifer Connelly, Bradley Cooper, Alec Greven December 10, 2008
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16 - 60Bill Hader, Jessica Szohr, Tony Bennett December 11, 2008
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16 - 61Don Rickles, John Leguizamo, Erran Baron Cohen December 12, 2008
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16 - 62Amy Adams, Eddie Izzard, John Legend December 15, 2008
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16 - 63Eva Mendes, Ken Mink, Fleet Foxes December 16, 2008
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16 - 64Jeff Goldblum, David Gregory, Charlie Viracola December 17, 2008
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16 - 65Matthew Broderick, Paul F. Tompkins, Little Big Town December 18, 2008
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16 - 66Jennifer Aniston, Judah Friedlander, Pilobolus December 19, 2008
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16 - 67Carson Daly, Steve Schirripa, Bela Fleck and the Flecktones December 22, 2008
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16 - 68Dustin Hoffman, Greg Giraldo, Old Crow Medicine Show December 23, 2008
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16 - 69Benicio Del Toro, Sarah Chalke, Doyle & Debbie January 05, 2009
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16 - 70Kate Hudson, Tim Daly, Bang Camaro January 06, 2009
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16 - 71Chris Meloni, Sheriff Joe Arpaio, The Derek Trucks Band January 07, 2009
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16 - 72Howie Mandel, Anthony Mackie, Lady Antebellum January 08, 2009
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16 - 73Daniel Radcliffe, Dr. Drew Pinsky, Eric Hutchinson January 12, 2009
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16 - 74Rosario Dawson, Donald Faison, Susan Tedeschi January 13, 2009
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16 - 75Salma Hayek, Paul Bettany, Patty Loveless January 14, 2009
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16 - 76Bob Costas, Fred Armisen, Robert Schimmel January 15, 2009
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16 - 77Teri Hatcher, Aries Spears, Q-Tip January 19, 2009
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16 - 78William H. Macy, Steve Nash, Los Straitjackets January 20, 2009
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16 - 79Meredith Viera, Marc Maron, Fall Out Boy January 21, 2009
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16 - 80Ron Howard,Eric McCormack & John Cassidy January 22, 2009
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16 - 81John C. Reilly, Jimmie Johnson, The Walkmen January 26, 2009
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16 - 82Matt Lauer, Steve Harvey, M83 January 27, 2009
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16 - 83Evangeline Lilly, Kevin Connolly, Cold War Kids January 28, 2009
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16 - 84Jon Stewart, Mary Lynn Rajskub, Mike Birbiglia January 29, 2009
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16 - 85Kathy Griffin, Paula Deen, Amy Lavere February 02, 2009
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16 - 86Seth Meyers, Johnny Knoxville, Zac Brown Band February 03, 2009
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16 - 87Jon Hamm, Ginnifer Goodwin, Theresa Andersson February 04, 2009
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16 - 88Brian Williams, Taraji P. Henson, Nate Bargatze February 05, 2009
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16 - 89Clive Owen, Judah Friedlander, Brett Dennen February 09, 2009
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16 - 90Norm MacDonald, Gordon Ramsay, Levon Helm February 10, 2009
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16 - 91Jimmy Fallon, Rose Byrne, John Pizzarelli February 11, 2009
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16 - 92Alec Baldwin, Eliza Dushku, They Might Be Giants February 12, 2009
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16 - 93Isla Fisher, The Jonas Brothers, Dan Auerbach February 13, 2009
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16 - 94Bob Saget, The Newno2 February 16, 2009
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16 - 95Jason Sudeikis February 17, 2009
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16 - 96Nathan Lane, Martha Stewart February 18, 2009
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16 - 97Jerry Seinfeld, Craig Bierko February 19, 2009
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16 - 98The Final Episode, The White Stripes February 20, 2009
